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Albiglutide is generated from a genetic fusion of two modified recombinant GLP-1 (736) molecules linked in tandem to recombinant human albumin (90), while dulaglutide is created by conjugating two GLP-1 (737) analogues to the Fc fragment of a modified monoclonal antibody (IgG4) via peptide ((Gly 4 Ser) 3 Ala) linker (91)
Addition of incretin therapy to metformin in type 2 diabetes
(Regulatory Document)
Where appropriate, aliquoting may help reduce repeated handling
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